Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812233 | 1.00 | TRPA1 (0.40) | TRPA1HPGDALDH1A1TDP1MAPT | |
| SCHEMBL812821 | 0.81 | TDP1 (0.40) | TRPA1HPGDALDH1A1TDP1MAPT | |
| SCHEMBL809522 | 0.81 | TDP1 (0.40) | TRPA1HPGDALDH1A1TDP1MAPT | |
| SCHEMBL2948740 | 0.74 | MAPT (0.39) | TRPA1HPGDALDH1A1TDP1MAPT | |
| SCHEMBL2436746 | 0.74 | MAPT (0.39) | TRPA1HPGDALDH1A1TDP1MAPT | |
| SCHEMBL10697600 | 0.74 | TDP1 (0.44) | HPGDALDH1A1TDP1MAPTGAA | |
| SCHEMBL2255542 | 0.73 | TDP1 (0.48) | HPGDALDH1A1TDP1MAPTGAA | |
| SCHEMBL2439065 | 0.72 | GSR (0.47) | TRPA1HPGDALDH1A1L3MBTL1RAB9A | |
| SCHEMBL2439069 | 0.72 | GSR (0.47) | TRPA1HPGDALDH1A1L3MBTL1RAB9A | |
| SCHEMBL812348 | 0.71 | HPGD (0.37) | HPGDALDH1A1MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228564-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-14 | — | — | US | disclosed |
| US-20140228564-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-14 | — | — | US | disclosed |
| US-20140228564-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-14 | — | — | US | disclosed |
| US-8680335-B2 | Processes of enantioselectively forming an aminoxy compound and an 1,2-oxazine compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-03-25 | — | — | US | disclosed |
| US-8680335-B2 | Processes of enantioselectively forming an aminoxy compound and an 1,2-oxazine compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-03-25 | — | — | US | disclosed |
| US-8680335-B2 | Processes of enantioselectively forming an aminoxy compound and an 1,2-oxazine compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-03-25 | — | — | US | disclosed |
| US-20110224429-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-09-15 | — | — | US | disclosed |
| US-20110224429-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-09-15 | — | — | US | disclosed |
| US-20110224429-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-09-15 | — | — | US | disclosed |
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| US-7279601-B2 | Optically active α-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1661885-A1 | OPTICALLY ACTIVE ALPHA-AMINOOXYKETONE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Tokyo University of Science (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | SCO2, CBR1, CBR3 | TRPA1 2709/4885HPGD 868/4885ALDH1A1 1287/4885 |
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | ALDH7A1, ASPH, KMO | TRPA1 1738/4885HPGD 205/4885ALDH1A1 71/4885 |
| US-20110224429-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | AHR, CYP2S1, CYP1A1 | TRPA1 2445/4885HPGD 1701/4885ALDH1A1 354/4885 |
| US-20140228564-A1 | PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND | AHR, CYP2S1, CYP1A1 | TRPA1 2445/4885HPGD 1701/4885ALDH1A1 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.