SCHEMBL809833

SCHEMBL809833

C=Cc1ccc(CCl)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.39
TRPA1 O75762 1/20 0.35
MAPT P10636 2/20 0.32
PKM P14618 1/20 0.32
ALOX5 P09917 2/20 0.32
PTGS1 P23219 2/20 0.32
PTGS2 P35354 2/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
PON1 P27169 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467225 1.00 TP53 (0.41) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL809528 0.84 TP53 (0.41) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL11834990 0.83 PTGS1 (0.41) ALOX5PTGS1PTGS2
SCHEMBL11834977 0.83 PTGS1 (0.41) ALOX5PTGS1PTGS2
SCHEMBL12802253 0.82 TDP1 (0.42) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL11073040 0.81 ALDH1A1 (0.43) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL18874549 0.80 TP53 (0.35) TP53TDP1ALDH1A1TRPA1
SCHEMBL15524799 0.80 TP53 (0.41) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL5115085 0.80 TDP1 (0.41) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL10124488 0.80 TP53 (0.41) TP53TDP1ALDH1A1TRPA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116272-A1 METHOD FOR PREPARING TERTIARY AMINES COMPRISING ETHYNYLBENZYL SUBSTITUENTS PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2017-07-06 WO claimed
EP-0036528-B1 BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-01-16 EP claimed
EP-3983418-B1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-11-05 EP disclosed
CN-113939522-B Organosilane, ionic organosilane, film composition and film 3M创新有限公司 2024-12-17 CN disclosed
US-12122797-B2 Organosilane, ionic organosilane, membrane composition, and membrane 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-10-22 US disclosed
US-20220251120-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE US DEPARTMENT OF ENERGY 2022-08-11 US disclosed
EP-3983418-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE 3M Innovative Properties Company (US) 2022-04-20 EP disclosed
CN-113939522-A Organosilane, ionic organosilane, film composition and film 3M创新有限公司 2022-01-14 CN disclosed
WO-2020254930-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-12-24 WO disclosed
WO-2017116272-A1 METHOD FOR PREPARING TERTIARY AMINES COMPRISING ETHYNYLBENZYL SUBSTITUENTS PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2017-07-06 WO disclosed
WO-2017116272-A1 METHOD FOR PREPARING TERTIARY AMINES COMPRISING ETHYNYLBENZYL SUBSTITUENTS PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2017-07-06 WO disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
US-20100160216-A1 ENHANCED TRANSPORT USING MEMBRANE DISRUPTIVE AGENTS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-06-24 US disclosed
US-7737108-B1 Enhanced transport using membrane disruptive agents UNIVERSITY OF WASHINGTON (US) 2010-06-15 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed
US-5138001-A Optical disc substrates; low birefringence, heat and moisture absorption resistance, high transparency TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-08-11 US disclosed
EP-0415729-A2 Vinylphenyl compound, process for the production thereof, polymerizable composition containing same, and crosslinked polymer formed therefrom TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
EP-0036528-B1 BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-01-16 EP disclosed
EP-0036528-A1 Butadiene-styrene-vinyl benzyl chloride terpolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-09-30 EP disclosed
US-4268642-A Butadiene-styrene-vinyl benzyl chloride terpolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251120-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE PHOSPHO1, ARRB1, OR51E2 TP53 3607/4885TDP1 1676/4885ALDH1A1 3218/4885
US-12122797-B2 Organosilane, ionic organosilane, membrane composition, and membrane PHOSPHO1, ARRB1, OR51E2 TP53 3607/4885TDP1 1676/4885ALDH1A1 3218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.