Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 3/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8102214 | 0.98 | ALDH1A1 (0.41) | ALDH1A1KLKB1PLK1ST14HDAC3 | |
| SCHEMBL8380879 | 0.78 | PTPN1 (0.40) | PLK1HDAC3MLYCDNPC1POLB | |
| SCHEMBL7266574 | 0.78 | ALDH1A1 (0.48) | ALDH1A1PLK1ST14F2POLB | |
| Hydrochloric Acid SCHEMBL8377317 | 0.77 | PTPN1 (0.39) | PLK1HDAC3MLYCDNPC1POLB | |
| Hydrochloric Acid SCHEMBL8505962 | 0.76 | CES2 (0.52) | NPC1RAB9A | |
| SCHEMBL4158704 | 0.76 | CA1 (0.48) | ALDH1A1PLK1ST14HDAC3SCN5A | |
| SCHEMBL8104313 | 0.74 | EPHX2 (0.41) | KLKB1 | |
| Hydrochloric Acid SCHEMBL8095878 | 0.73 | EPHX2 (0.40) | KLKB1F2F10 | |
| SCHEMBL14089940 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8341384 | 0.73 | TRPV1 (0.41) | ALDH1A1KLKB1HDAC1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702001-B1 | Trifluoro-propyl-substituted benzoylguanidinens and their use as medicament or diagnostic agent | HOECHST AG (DE) | 2000-08-23 | — | — | EP | claimed |
| US-5869531-A | NO UNDESIREABLE SALIDIURETIC PROPERTIES; TREATING ISCHEMIA INDUCED DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | claimed |
| US-5869531-A | NO UNDESIREABLE SALIDIURETIC PROPERTIES; TREATING ISCHEMIA INDUCED DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |