Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088800 | 0.85 | HCAR3 (0.47) | HCAR3HTTMAPTKMT2AALDH1A1 | |
| SCHEMBL944514 | 0.84 | TDP1 (0.44) | HCAR3HTTMAPTKMT2AALDH1A1 | |
| SCHEMBL31257496 | 0.82 | KMT2A (0.42) | MAPTKMT2AALDH1A1TDP1ATM | |
| SCHEMBL26790809 | 0.81 | TDP1 (0.47) | ALDH1A1TDP1ATMLMNATSHR | |
| SCHEMBL30273906 | 0.81 | ALDH1A1 (0.39) | HCAR3MAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL25339286 | 0.81 | ALDH1A1 (0.39) | HCAR3MAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL26973962 | 0.80 | MAPT (0.51) | HTTMAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL626311 | 0.78 | ALDH1A1 (0.46) | MAPTKMT2AALDH1A1TDP1LMNA | |
| SCHEMBL24246357 | 0.76 | KCNQ3 (0.48) | HTTMAPTKMT2AALDH1A1POLB | |
| SCHEMBL8097768 | 0.75 | HCAR3 (0.49) | HCAR3HTTMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743848-B1 | 2-FLUORO-6-NITROANILINES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |