Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088800 | 0.91 | HCAR3 (0.47) | HCAR3LMNAMAPTL3MBTL1MAPK1 | |
| SCHEMBL28995916 | 0.85 | MAPT (0.42) | HCAR3LMNAMAPTL3MBTL1MAPK1 | |
| SCHEMBL8103843 | 0.78 | RAB9A (0.64) | HCAR3LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL6118560 | 0.75 | TDP1 (0.52) | HCAR3LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL4090213 | 0.75 | HCAR3 (0.61) | HCAR3LMNAMAPTL3MBTL1MAPK1 | |
| SCHEMBL31481963 | 0.75 | MAPT (0.57) | HCAR3LMNAMAPTL3MBTL1MAPK1 | |
| SCHEMBL3512219 | 0.75 | MAPT (0.57) | HCAR3LMNAMAPTL3MBTL1MAPK1 | |
| SCHEMBL3450046 | 0.75 | TDP1 (0.44) | HCAR3LMNAMAPTL3MBTL1MAPK1 | |
| SCHEMBL8095455 | 0.75 | HCAR3 (0.45) | HCAR3LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL28995911 | 0.73 | MAPT (0.41) | HCAR3LMNAMAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743848-B1 | 2-FLUORO-6-NITROANILINES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |