Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.55 |
| ▸ | PAK4 | O96013 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130504 | 0.83 | PLK4 (0.57) | PLK4PAK4PDE2APDPK1MKNK1 | |
| SCHEMBL24672488 | 0.80 | PLK4 (0.58) | PLK4PAK4PDE2APDPK1MKNK1 | |
| SCHEMBL27227932 | 0.79 | PLK4 (0.54) | PLK4PAK4PDE2APDPK1HTR2C | |
| SCHEMBL30861057 | 0.79 | PLK4 (0.54) | PLK4PAK4PDE2APDPK1HTR2C | |
| SCHEMBL560806 | 0.78 | RET (0.52) | PLK4PAK4PDE2APDPK1MKNK1 | |
| SCHEMBL53863 | 0.78 | PLK4 (0.47) | PLK4PAK4PDE2AMKNK1RET | |
| SCHEMBL3754341 | 0.78 | HPGDS (0.53) | PLK4PAK4PDE2AHTR2CHTR2A | |
| SCHEMBL13896217 | 0.76 | MAPK1 (0.59) | PLK4PAK4PDE2AMKNK1HTR2C | |
| SCHEMBL22282188 | 0.76 | ALDH1A1 (0.59) | PLK4PAK4PDE2AHTR2CHTR2A | |
| SCHEMBL22282069 | 0.75 | HPGDS (0.61) | PLK4PAK4PDE2AHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000038389-A | PYRAZOLOPYRIMIDINES AND XANTHINE OXIDASE | YAMASA SHOYU CO LTD | 2000-02-08 | — | — | JP | disclosed |