Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 5/20 | 0.58 |
| ▸ | PAK4 | O96013 | 4/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009126 | 0.85 | PLK4 (0.45) | PLK4PAK4PDE2A | |
| SCHEMBL130504 | 0.82 | PLK4 (0.57) | PLK4PAK4PDE2APDPK1HTR2C | |
| SCHEMBL8095697 | 0.80 | PLK4 (0.55) | PLK4PAK4PDE2APDPK1HTR2C | |
| SCHEMBL30861057 | 0.78 | PLK4 (0.54) | PLK4PAK4PDE2APDPK1HTR2C | |
| SCHEMBL29564085 | 0.77 | PLK4 (0.46) | PLK4PAK4PDE2ABTK | |
| SCHEMBL16052607 | 0.77 | PLK4 (0.46) | PLK4PAK4PDE2ABTK | |
| SCHEMBL22282188 | 0.76 | ALDH1A1 (0.59) | PLK4PAK4PDE2AHTR2CHTR2A | |
| SCHEMBL22282069 | 0.74 | HPGDS (0.61) | PLK4PAK4PDE2AHTR2CHTR2A | |
| SCHEMBL29705692 | 0.74 | HPGDS (0.61) | PLK4PAK4PDE2AHTR2CHTR2A | |
| SCHEMBL61883 | 0.74 | PLK4 (0.53) | PLK4PAK4PDE2APDPK1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |