Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211340 | 1.00 | MEN1 (0.54) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL6213333 | 0.93 | MEN1 (0.48) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL27328908 | 0.87 | FKBP1A (0.50) | KDM4EMAPK1FKBP1A | |
| SCHEMBL79066 | 0.86 | F10 (0.51) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL29671561 | 0.84 | FKBP1A (0.47) | KMT2AALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL27551310 | 0.84 | FKBP1A (0.47) | KMT2AALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL14711760 | 0.82 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL14711764 | 0.82 | F10 (0.47) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL4996049 | 0.82 | MEN1 (0.55) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL6214398 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |