Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27551310 | 1.00 | FKBP1A (0.47) | FKBP1AOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL26246339 | 0.95 | SCN9A (0.48) | FKBP1AOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL29035348 | 0.95 | SCN9A (0.48) | FKBP1AOPRM1OPRD1OPRK1OGFRL1 | |
| Hydrochloric Acid SCHEMBL29289926 | 0.94 | SCN9A (0.47) | FKBP1AOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL29671593 | 0.89 | KMT2A (0.47) | FKBP1ALTA4HSMN1; SMN2KMT2ASLC6A4 | |
| SCHEMBL2770443 | 0.89 | KMT2A (0.47) | FKBP1ALTA4HSMN1; SMN2KMT2ASLC6A4 | |
| SCHEMBL29349017 | 0.87 | ALDH1A1 (0.46) | FKBP1ABACE1KMT2AMMP2ANPEP | |
| SCHEMBL29349018 | 0.85 | ALDH1A1 (0.44) | FKBP1AOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL29349019 | 0.85 | SLC6A3 (0.44) | FKBP1AOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL8095933 | 0.84 | MEN1 (0.54) | FKBP1ASMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3930849-B1 | THIAZOLE DERIVATIVES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | FKBP1A 1409/4885OPRM1 4412/4885OPRD1 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.