SCHEMBL809616

SCHEMBL809616

Nc1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(N)cc4)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.73
HTR6 P50406 3/20 0.73
CYP3A4 P08684 2/20 0.73
LMNA P02545 1/20 0.73
MPO P05164 1/20 0.73
CYP2C9 P11712 1/20 0.73
ALDH1A1 P00352 5/20 0.64
TDP1 Q9NUW8 3/20 0.64
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
HTT P42858 2/20 0.58
PKM P14618 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MAOA P21397 2/20 0.54
MMP2 P08253 4/20 0.53
MMP9 P14780 4/20 0.53
MMP3 P08254 1/20 0.53
MMP8 P22894 1/20 0.53
MMP14 P50281 1/20 0.53
MAPT P10636 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65653 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
Dapsone SCHEMBL11226869 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL7461906 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL203972 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL38664337 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL7460220 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL7463604 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL25410355 0.94 HTR6 (0.64) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL8905322 0.94 HTR6 (0.64) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL9472814 0.92 MAOA (0.63) TSHRHTR6CYP3A4LMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4036159-B1 POLYIMIDE-BASED FILM HAVING EXCELLENT SURFACE EVENNESS AND METHOD FOR PRODUCING SAME KOLON INC (KR) 2025-08-06 EP claimed
EP-3877447-B1 COMPOSITION OF PHTHALONITRILE RESIN MATRIX FOR POLYMER COMPOSITE MATERIALS, METHOD FOR FABRICATION THEREOF, METHOD FOR MANUFACTURING OF POLYMER COMPOSITE MATERIAL, AND MATERIAL OBTAINED BY THIS METHOD JOINT STOCK COMPANY (RU) 2024-07-17 EP claimed
EP-3919541-B1 EPOXY RESIN SOLUTION UNITIKA LTD (JP) 2023-06-21 EP claimed
EP-3368198-B1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2022-07-06 EP claimed
EP-3150655-B1 POLYIMIDE-BASED LIQUID AND POLYIMIDE-BASED FILM PRODUCED USING SAME LG CHEMICAL LTD (KR) 2021-05-05 EP claimed
EP-2766920-B1 SPIN-ON CARBON COMPOSITIONS FOR LITHOGRAPHIC PROCESSING BREWER SCIENCE INC (US) 2020-12-02 EP claimed
EP-2666607-B1 TIRE BLADDER DENKA COMPANY LTD (JP) 2018-03-14 EP claimed
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
EP-1449881-B1 ACRYLIC RUBBER COMPOSITION DENKI KAGAKU KOGYO KK (JP) 2014-06-18 EP claimed
US-8470435-B2 Epdxy resin for prepreg, prepreg, fiber-reinforced composite material, and methods for production thereof MITSUBISHI RAYON CO., LTD. (JP) 2013-06-25 US claimed
EP-0716113-B1 Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof TOHO RAYON KK (JP) 2000-01-19 EP claimed
EP-0559667-B1 THERMOPLASTICALLY PROCESSABLE AROMATIC POLYETHER AMIDE HOECHST AG (DE) 1997-04-09 EP claimed
EP-0583958-B1 Polyimide/aliphatic polyester copolymers EXXON RESEARCH ENGINEERING CO (US) 1996-10-02 EP claimed
EP-0489429-B1 Method of producing flexible printed-circuit board covered with cover layer HITACHI CHEMICAL CO LTD (JP) 1996-06-19 EP claimed
EP-0424041-B1 Membranes obtained from copolymers of polyimides and aliphatic polyesters. EXXON RESEARCH ENGINEERING CO (US) 1996-03-20 EP claimed
EP-0459809-B1 Polyimidosiloxane resin and composition thereof and method of applying same UBE INDUSTRIES (JP) 1995-02-08 EP claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
US-5252703-A Heat resistant, dielectric, flexibility UBE INDUSTRIES, LTD. (JP) 1993-10-12 US claimed
WO-1992009648-A1 THERMOPLASTICALLY PROCESSABLE AROMATIC POLYETHER AMIDE HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-11 WO claimed
EP-0459809-A1 Polyimidosiloxane resin and composition thereof and method of applying same UBE INDUSTRIES, LTD. (JP) 1991-12-04 EP claimed