SCHEMBL203972

SCHEMBL203972

Nc1ccc(Oc2ccc(Oc3ccc(S(=O)(=O)c4ccc(Oc5ccc(Oc6ccc(N)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.73
HTR6 P50406 3/20 0.73
CYP3A4 P08684 2/20 0.73
LMNA P02545 1/20 0.73
MPO P05164 1/20 0.73
CYP2C9 P11712 1/20 0.73
ALDH1A1 P00352 5/20 0.64
TDP1 Q9NUW8 3/20 0.64
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
HTT P42858 2/20 0.58
PKM P14618 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MAOA P21397 2/20 0.54
MMP2 P08253 4/20 0.53
MMP9 P14780 4/20 0.53
MMP3 P08254 1/20 0.53
MMP8 P22894 1/20 0.53
MMP14 P50281 1/20 0.53
MAPT P10636 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65653 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
Dapsone SCHEMBL11226869 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL7461906 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL38664337 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL7460220 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL7463604 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL809616 1.00 TSHR (0.73) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL25410355 0.94 HTR6 (0.64) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL8905322 0.94 HTR6 (0.64) TSHRHTR6CYP3A4LMNAMPO
SCHEMBL9472814 0.92 MAOA (0.63) TSHRHTR6CYP3A4LMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-02-12 US claimed
US-5459233-A High temperature engineering aromatic polyimides MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-17 US claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 US claimed
JP-2178328-A None JP disclosed
JP-1240564-A None JP disclosed
JP-3031323-A None JP disclosed
JP-1009227-A None JP disclosed
JP-1009226-A None JP disclosed
JP-8127656-A None JP disclosed
CN-117241942-B Laminate body 东洋纺株式会社 2026-05-19 CN disclosed
JP-H01240564-A POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEM INC 1989-09-26 JP disclosed
EP-0333406-A1 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-20 EP disclosed
EP-0330505-A1 Process for preparing polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
JP-S649227-A POLYIMIDE MITSUI TOATSU CHEMICALS 1989-01-12 JP disclosed
JP-S649226-A POLYIMIDE AND HEAT-RESISTANT ADHESIVE COMPRISING SAME MITSUI TOATSU CHEMICALS 1989-01-12 JP disclosed
EP-0297808-A1 Polyimide and high-temperature adhesive thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-01-04 EP disclosed
EP-0297808-A1 Polyimide and high-temperature adhesive thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom AOC1, INMT, PRMT6 TSHR 4468/4885HTR6 1596/4885CYP3A4 4558/4885
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 TSHR 4415/4885HTR6 4622/4885CYP3A4 4322/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 TSHR 4346/4885HTR6 4647/4885CYP3A4 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.