Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555957 | 0.83 | ERBB2 (0.71) | EGFRERBB2 | |
| SCHEMBL8093486 | 0.81 | EGFR (0.57) | EGFRERBB2 | |
| SCHEMBL8081967 | 0.80 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL9910666 | 0.79 | EGFR (0.66) | EGFRERBB2 | |
| SCHEMBL9910675 | 0.79 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL29690398 | 0.78 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL30513 | 0.78 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL7243965 | 0.76 | EGFR (0.79) | EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL7243031 | 0.75 | EGFR (0.77) | EGFRERBB2 | |
| SCHEMBL27680332 | 0.75 | EGFR (0.68) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153617-A | Irreversible bicyclic inhibitors of tyrosine kinases | WARNER-LAMBERT COMPANY (US) | 2000-11-28 | — | — | US | claimed |
| WO-1999006396-A1 | IRREVERSIBLE BICYCLIC INHIBITORS OF TYROSINE KINASES | WARNER-LAMBERT COMPANY (US) | 1999-02-11 | — | — | WO | claimed |
| US-6153617-A | Irreversible bicyclic inhibitors of tyrosine kinases | WARNER-LAMBERT COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| WO-1999006396-A1 | IRREVERSIBLE BICYCLIC INHIBITORS OF TYROSINE KINASES | WARNER-LAMBERT COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |