Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096310 | 1.00 | CTSL (0.57) | CTSLGAAMAPTL3MBTL1ATM | |
| SCHEMBL8096343 | 0.84 | GAA (0.53) | CTSLGAAMAPTL3MBTL1 | |
| SCHEMBL8096338 | 0.84 | GAA (0.53) | CTSLGAAMAPTL3MBTL1 | |
| SCHEMBL8038231 | 0.83 | ATM (0.58) | CTSLATMMETTL3CTSB | |
| SCHEMBL8038235 | 0.83 | ATM (0.58) | CTSLATMMETTL3CTSB | |
| SCHEMBL5146320 | 0.83 | CTSL (0.50) | CTSLGAAMAPTL3MBTL1ATM | |
| SCHEMBL7165299 | 0.81 | CTSL (0.53) | CTSLGAAMAPTL3MBTL1 | |
| SCHEMBL941478 | 0.80 | CTSL (0.66) | CTSLGAAMAPTL3MBTL1ATM | |
| SCHEMBL941477 | 0.80 | CTSL (0.66) | CTSLGAAMAPTL3MBTL1ATM | |
| SCHEMBL5146258 | 0.80 | CTSL (0.58) | CTSLGAAMAPTL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034272-A | CARDIOVASCULAR DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-03-07 | — | — | US | claimed |
| WO-1998057929-A1 | ELEVATION OF HDL CHOLESTEROL BY N-[4-[ (AMINOTHIOXOMETHYL) HYDRAZONO] -4-ARYLBUTYL]AMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | claimed |
| US-6034272-A | CARDIOVASCULAR DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-03-07 | — | — | US | disclosed |