Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 9/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155672 | 0.82 | KDM2B (0.71) | LMNATP53MAPTL3MBTL1MGLL | |
| Hydrochloric Acid SCHEMBL6992831 | 0.81 | MGLL (0.53) | LMNATP53MAPTL3MBTL1MGLL | |
| Hydrochloric Acid SCHEMBL3839082 | 0.81 | MGLL (0.53) | LMNATP53MAPTL3MBTL1MGLL | |
| Hydrochloric Acid SCHEMBL3839088 | 0.81 | MGLL (0.53) | LMNATP53MAPTL3MBTL1MGLL | |
| Hydrochloric Acid SCHEMBL7229019 | 0.81 | MGLL (0.53) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL6395815 | 0.81 | KCNH2 (0.54) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL11747892 | 0.79 | KCNH2 (0.64) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL14638479 | 0.79 | MGLL (0.61) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL9380802 | 0.79 | KCNH2 (0.64) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL12721473 | 0.79 | MGLL (0.54) | LMNATP53MAPTL3MBTL1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |