Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | MGLL | Q99685 | 5/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380802 | 0.88 | KCNH2 (0.64) | KDM2BLMNATP53MAPTL3MBTL1 | |
| SCHEMBL11747892 | 0.88 | KCNH2 (0.64) | KDM2BLMNATP53MAPTL3MBTL1 | |
| SCHEMBL10928975 | 0.87 | HTR2A (0.72) | HTR2AHTR7HTR2CHTR6 | |
| SCHEMBL24135454 | 0.86 | KCNH2 (0.79) | LMNAKCNH2DRD2MEN1KMT2A | |
| SCHEMBL11519875 | 0.85 | KCNH2 (0.62) | KDM2BLMNATP53MAPTL3MBTL1 | |
| SCHEMBL3391998 | 0.84 | MGLL (0.69) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL17919889 | 0.83 | KDM2B (1.00) | KDM2BMEN1KMT2A | |
| SCHEMBL11621419 | 0.83 | DRD2 (0.65) | KCNH2MGLLDRD2MEN1KMT2A | |
| SCHEMBL8096313 | 0.82 | LMNA (0.60) | KDM2BLMNATP53MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11617320 | 0.82 | DRD2 (0.63) | KCNH2MGLLDRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |