Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155672 | 0.88 | KDM2B (0.71) | KCNH2MGLLLMNATP53MAPT | |
| SCHEMBL11747892 | 0.88 | KCNH2 (0.64) | KCNH2MGLLLMNATP53MAPT | |
| SCHEMBL11519875 | 0.85 | KCNH2 (0.62) | KCNH2MGLLLMNATP53MAPT | |
| SCHEMBL8714691 | 0.85 | HTR2A (0.74) | LMNAHTR2AHTR7HTR2CHTR6 | |
| SCHEMBL11621419 | 0.83 | DRD2 (0.65) | KCNH2MGLLMEN1KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL11617320 | 0.82 | DRD2 (0.63) | KCNH2MGLLMEN1KMT2AHTR2A | |
| SCHEMBL14638479 | 0.82 | MGLL (0.61) | KCNH2MGLLLMNATP53MAPT | |
| SCHEMBL12642631 | 0.81 | KCNH2 (0.74) | KCNH2MGLLLMNATP53MAPT | |
| SCHEMBL3391998 | 0.81 | MGLL (0.69) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL5468238 | 0.80 | KCNH2 (0.56) | KCNH2MGLLLMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401707-B1 | Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity | DAIICHI SEIYAKU CO (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5232924-A | Cardiovascular disorders | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0401707-A1 | Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |