Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945423 | 0.82 | HTR1D (0.50) | SMN1; SMN2NCF1LTA4HKCNH2HTR4 | |
| SCHEMBL6153469 | 0.79 | GAA (0.80) | GAAMEN1KMT2ASMN1; SMN2LTA4H | |
| SCHEMBL8095852 | 0.79 | CCR3 (0.47) | MEN1KMT2ASMN1; SMN2DRD2HTR2A | |
| SCHEMBL8094653 | 0.77 | PDE2A (0.47) | GAABCHEACHENCF1 | |
| SCHEMBL3967865 | 0.76 | ADAM17 (0.57) | GAAMEN1KMT2ASMN1; SMN2ADAM17 | |
| SCHEMBL13945422 | 0.74 | KDM4E (0.50) | MEN1KMT2ANCF1 | |
| SCHEMBL22628913 | 0.74 | GAA (0.49) | GAAMEN1KMT2ASMN1; SMN2LTA4H | |
| SCHEMBL14032717 | 0.74 | KDM1A (0.56) | GAABCHEACHEKDM1ADRD2 | |
| SCHEMBL27533416 | 0.73 | CCR3 (0.68) | GAAMEN1KMT2ABCHEACHE | |
| SCHEMBL8104188 | 0.73 | HRH1 (0.47) | MEN1KMT2ABCHEACHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |