Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096499 | 0.79 | GAA (0.53) | MEN1KMT2AHTR2AHTR4DRD2 | |
| SCHEMBL13945353 | 0.77 | S1PR5 (0.43) | KDM4EALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL13945391 | 0.76 | S1PR5 (0.39) | KDM4EALDH1A1ATMPOLBTSHR | |
| SCHEMBL8095854 | 0.74 | KDM4E (0.46) | CCR3KDM4EMEN1KMT2AGRIN1 | |
| SCHEMBL8094653 | 0.73 | PDE2A (0.47) | KDM4EHTTALDH1A1MAPTATM | |
| SCHEMBL8102227 | 0.72 | GRIN1 (0.42) | CCR3KDM4EMEN1KMT2AGRIN1 | |
| SCHEMBL8091662 | 0.70 | HRH1 (0.47) | CCR3KMT2AALDH1A1HRH1 | |
| SCHEMBL13945374 | 0.69 | DCPS (0.60) | ATMHTR4 | |
| SCHEMBL8092993 | 0.69 | HTR2B (0.44) | CCR3GRIN1GRIN2BATMHTR2A | |
| SCHEMBL8101941 | 0.68 | KDM4E (0.45) | KDM4EMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |