Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914307 | 0.87 | TP53 (0.47) | TP53NR3C2ACHEMAPT | |
| SCHEMBL8096601 | 0.83 | MEN1 (0.47) | NR3C2MAPT | |
| SCHEMBL8084184 | 0.79 | MAPT (0.63) | TP53MAPT | |
| SCHEMBL6945482 | 0.78 | CACNA1B (0.48) | MAPT | |
| SCHEMBL8914575 | 0.77 | TP53 (0.49) | TP53NR3C2ACHEMAPT | |
| Imidazole SCHEMBL8914572 | 0.77 | TP53 (0.47) | TP53NR3C2ACHEMAPT | |
| SCHEMBL6951645 | 0.75 | MEN1 (0.56) | MAPT | |
| SCHEMBL7887451 | 0.75 | NR1I2 (0.55) | TP53MAPT | |
| SCHEMBL6953550 | 0.73 | CACNA1F (0.50) | TP53NR3C2MAPT | |
| SCHEMBL8913434 | 0.72 | TP53 (0.53) | TP53NR3C2ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066655-A | FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, IN PARTICULAR AS CEREBRAL THERAPEUTICS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| US-5731333-A | LEARNING AND MEMORY ENHANCEMENT, ANTIDEPRESSANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |