Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951645 | 0.88 | MEN1 (0.56) | MEN1KMT2AKDM4ERAB9AMAPT | |
| SCHEMBL6950016 | 0.86 | ALOX15 (0.50) | CACNA1BKDM4EMAPTCACNA1FCACNA1D | |
| SCHEMBL6945817 | 0.82 | ALOX15 (0.51) | CACNA1BMEN1KMT2AKDM4EMAPT | |
| SCHEMBL7887451 | 0.81 | NR1I2 (0.55) | CACNA1BMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL6947853 | 0.80 | ALOX15 (0.59) | CACNA1BMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL6948535 | 0.80 | CACNA1B (0.53) | CACNA1BMEN1KMT2AKDM4EMAPT | |
| SCHEMBL8096601 | 0.79 | MEN1 (0.47) | MEN1KMT2AKDM4EMAPTCACNA1F | |
| SCHEMBL8913556 | 0.79 | MEN1 (0.47) | CACNA1BMEN1KMT2AKDM4EMAPT | |
| SCHEMBL8096562 | 0.78 | TP53 (0.52) | MAPT | |
| SCHEMBL8914307 | 0.77 | TP53 (0.47) | KDM4ERAB9AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |