Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100065 | 0.83 | TP53 (0.51) | TP53MAPTNR3C2ACHEL3MBTL1 | |
| SCHEMBL8100090 | 0.81 | TP53 (0.54) | TP53MAPTNR3C2ACHEL3MBTL1 | |
| SCHEMBL6953550 | 0.80 | CACNA1F (0.50) | TP53MAPTNR3C2L3MBTL1 | |
| SCHEMBL9236145 | 0.80 | TP53 (0.44) | TP53MAPTNR3C2 | |
| SCHEMBL6953510 | 0.77 | SMN1; SMN2 (0.56) | TP53TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6948567 | 0.76 | SMN1; SMN2 (0.57) | TP53SMN1; SMN2 | |
| SCHEMBL6945817 | 0.76 | ALOX15 (0.51) | TP53MAPTADORA3 | |
| SCHEMBL8913648 | 0.75 | ADORA3 (0.52) | TP53MAPTTDP1SMN1; SMN2ADORA3 | |
| SCHEMBL6952565 | 0.75 | ALOX15 (0.61) | TP53MAPT | |
| SCHEMBL8914307 | 0.75 | TP53 (0.47) | TP53MAPTNR3C2TDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658934-A | Aryl-substituted alkoxycarbonyl-1,4-dihydropyridine-5-carboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |