Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245462 | 0.81 | MAPT (0.60) | TP53MAPT | |
| Imidazole SCHEMBL8914572 | 0.78 | TP53 (0.47) | TP53ACHEMAPTNR3C2 | |
| SCHEMBL8096562 | 0.77 | TP53 (0.52) | TP53ACHEMAPTNR3C2 | |
| SCHEMBL8914307 | 0.73 | TP53 (0.47) | TP53ACHEMAPTNR3C2 | |
| SCHEMBL6945801 | 0.72 | MAPT (0.50) | TP53MAPT | |
| SCHEMBL7887451 | 0.71 | NR1I2 (0.55) | TP53MAPT | |
| SCHEMBL8912934 | 0.65 | CYP2C9 (0.49) | TP53ACHEMAPTNR3C2 | |
| SCHEMBL10729302 | 0.64 | CYP2C9 (0.66) | TP53MAPT | |
| SCHEMBL10726831 | 0.64 | CYP2C9 (0.66) | TP53MAPT | |
| SCHEMBL27424745 | 0.64 | POLB (0.42) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658934-A | Aryl-substituted alkoxycarbonyl-1,4-dihydropyridine-5-carboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |