Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GALE | Q14376 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096761 | 0.79 | S1PR4 (0.43) | NR1I2ADORA3SLC6A2SLC6A3LMNA | |
| SCHEMBL8832605 | 0.76 | LMNA (0.38) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL3757554 | 0.63 | NPC1 (0.65) | LMNANPC1 | |
| SCHEMBL28105594 | 0.62 | MPO (0.47) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL28094808 | 0.60 | NR1I2 (0.39) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL27382746 | 0.60 | NR1I2 (0.47) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL13019830 | 0.60 | LMNA (0.39) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL3757553 | 0.58 | NR1I2 (0.40) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL5162446 | 0.58 | NR1I2 (0.41) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL13019313 | 0.58 | CSNK2A1 (0.50) | NR1I2ADRA2AADORA3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700951-B1 | Polyorganosiloxane and process for producing the same | SHOWA DENKO KK (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0700951-A1 | Polyorganosiloxane and process for producing the same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5491203-A | COMPRISES POLYSILSESQUIOXANE STRUCTURE; HAS METHYL GROUP AND A REACTIVE GROUP ON SIDE CHAINS; SUITABLE AS POLYMER MODIFIER; CROSSLINKING; COATINGS | SHOWA DENKO K. K. (JP) | 1996-02-13 | — | — | US | disclosed |