Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934985 | 0.89 | KCNA5 (0.42) | ALOX5KCNA5ALDH1A1KMT2AMEN1 | |
| SCHEMBL6937352 | 0.88 | EPHX1 (0.51) | EPHX1ALOX5TRPM8KCNA5ALDH1A1 | |
| SCHEMBL6063192 | 0.73 | CYP2C19 (0.47) | EPHX1ALOX5ALDH1A1TDP1KMT2A | |
| SCHEMBL6798718 | 0.73 | CYP2C19 (0.47) | EPHX1ALOX5ALDH1A1TDP1KMT2A | |
| SCHEMBL6939334 | 0.72 | MMP8 (0.47) | KCNA5ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL12718845 | 0.71 | EPHX1 (0.59) | EPHX1ALOX5ALDH1A1LMNAKDM4E | |
| SCHEMBL11568787 | 0.70 | KMT2A (0.46) | ALDH1A1TDP1KMT2AMEN1AKR1C3 | |
| SCHEMBL1343883 | 0.70 | FFAR1 (0.51) | KMT2A | |
| SCHEMBL9556420 | 0.70 | FFAR1 (0.51) | KMT2A | |
| SCHEMBL27862777 | 0.70 | FFAR1 (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |