Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096598 | 0.88 | EPHX1 (0.41) | EPHX1ALOX5TRPM8KCNA5GAA | |
| SCHEMBL6939334 | 0.81 | MMP8 (0.47) | KCNA5GAASMN1; SMN2MMP8MEN1 | |
| SCHEMBL6343341 | 0.78 | EPHX1 (0.49) | EPHX1ALOX5GAASMN1; SMN2MMP9 | |
| SCHEMBL1582847 | 0.78 | TRPM8 (0.49) | TRPM8KCNA5GAASMN1; SMN2MEN1 | |
| SCHEMBL12718845 | 0.78 | EPHX1 (0.59) | EPHX1ALOX5SMN1; SMN2MMP9MMP8 | |
| SCHEMBL2587234 | 0.77 | EPHX1 (0.63) | EPHX1GAASMN1; SMN2MMP9MMP8 | |
| SCHEMBL3353282 | 0.77 | EPHX1 (0.63) | EPHX1GAASMN1; SMN2MMP9MMP8 | |
| SCHEMBL9983066 | 0.77 | KCNA5 (0.48) | KCNA5GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7062913 | 0.76 | EPHX1 (0.46) | EPHX1ALOX5GAASMN1; SMN2MMP9 | |
| Hydrochloric Acid SCHEMBL3353959 | 0.75 | EPHX1 (0.61) | EPHX1GAASMN1; SMN2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-B1 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |