Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093886 | 0.93 | TAAR1 (0.40) | LTA4HLDHALDHBCNR1CNR2 | |
| SCHEMBL8102088 | 0.91 | TLR8 (0.42) | HTR2ALDHALDHBCNR1CNR2 | |
| SCHEMBL8095678 | 0.90 | CALM1 (0.44) | HTR2ALTA4HLDHALDHBBCL2 | |
| SCHEMBL8099932 | 0.89 | TLR8 (0.47) | HTR2ACNR1CNR2 | |
| SCHEMBL8099971 | 0.88 | TLR8 (0.46) | HTR2ACYP3A4TSHRCNR1CNR2 | |
| SCHEMBL8100554 | 0.88 | TLR8 (0.46) | HTR2ACYP3A4TSHRCNR1CNR2 | |
| SCHEMBL8094286 | 0.88 | TLR8 (0.46) | HTR2ACYP3A4TSHRCNR1CNR2 | |
| SCHEMBL8099386 | 0.87 | HTR2A (0.42) | HTR2ALTA4HCYP3A4CYP2D6TSHR | |
| SCHEMBL8101085 | 0.86 | LTA4H (0.47) | HTR2ALTA4HLDHALDHBCNR1 | |
| SCHEMBL8101996 | 0.84 | LTA4H (0.44) | HTR2ALTA4HLDHALDHBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |