Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567849 | 0.94 | TAAR1 (0.50) | TAAR1HRH3DAOIDO1ACHE | |
| SCHEMBL168757 | 0.92 | TAAR1 (0.65) | TAAR1HRH3DAOIDO1ACHE | |
| SCHEMBL29462896 | 0.92 | TAAR1 (0.65) | TAAR1HRH3DAOIDO1ACHE | |
| SCHEMBL5424543 | 0.89 | MTNR1A (0.47) | TAAR1MTNR1AMTNR1B | |
| SCHEMBL8096717 | 0.89 | TAAR1 (0.53) | TAAR1HRH3DAOIDO1XIAP | |
| SCHEMBL8093858 | 0.87 | TAAR1 (0.52) | TAAR1HRH3 | |
| SCHEMBL8095815 | 0.85 | LPL (0.53) | TAAR1 | |
| SCHEMBL8098390 | 0.85 | LPL (0.53) | TAAR1 | |
| SCHEMBL8086306 | 0.85 | LPL (0.53) | TAAR1 | |
| SCHEMBL8099663 | 0.85 | MTNR1A (0.49) | LTA4HMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |