SCHEMBL8096947

SCHEMBL8096947

CC1(c2ccccc2)CSCN1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
OPRM1 P35372 2/20 0.33
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33
BACE1 P56817 2/20 0.32
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
PAX8 Q06710 1/20 0.31
MCL1 Q07820 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CHRNB2 P17787 1/20 0.31
SLC6A2 P23975 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1071202 0.73 HTR2A (0.41) MMP2MMP9KDM4EMAPTOPRM1
SCHEMBL6544207 0.67 OPRM1 (0.44) MMP2MMP9KDM4EMAPTOPRM1
SCHEMBL21312268 0.65 OPRM1 (0.42) OPRM1OPRK1OPRL1HTR2A
SCHEMBL15995122 0.65 OPRM1 (0.42) OPRM1OPRK1OPRL1HTR2A
SCHEMBL15995119 0.65 OPRM1 (0.42) OPRM1OPRK1OPRL1HTR2A
SCHEMBL15656326 0.64 OPRM1 (0.41) MMP2MMP9OPRM1OPRK1OPRL1
SCHEMBL12071340 0.64 OPRM1 (0.41) MMP2MMP9OPRM1OPRK1OPRL1
SCHEMBL4534192 0.64 HTR2A (0.47) MMP2MMP9KDM4EMAPTOPRM1
SCHEMBL10708233 0.64 OPRM1 (0.41) OPRM1OPRK1OPRL1SLC6A2SLC6A3
SCHEMBL6185187 0.64 MMP2 (0.42) MMP2MMP9KDM4EMAPTOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713132-B1 Chemical sensitisation of silver halide emulsions EASTMAN KODAK CO (US) 2000-12-20 EP disclosed
US-5604084-A ADDING SULFUR RELEASING ORGANIC POLYMER HAVING MULTIPLE SULFUR RELEASING GROUPS IMATION CORP. (US) 1997-02-18 US disclosed
EP-0713132-A1 Chemical sensitisation of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-22 EP disclosed