SCHEMBL8096967

SCHEMBL8096967

COC(=O)Oc1ccc(OC(=O)OC)nc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACACB O00763 16/20 0.42
ACACA Q13085 9/20 0.42
NNMT P40261 1/20 0.40
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869465 0.91 ACACB (0.40) ACACBACACANNMTLMNAKMT2A
SCHEMBL7862661 0.90 KDM4E (0.39) ACACBACACALMNAMEN1KMT2A
SCHEMBL9199740 0.86 LMNA (0.44) NNMTLMNAMEN1KMT2A
SCHEMBL9199674 0.85 ACACB (0.39) ACACBACACAMEN1KMT2A
SCHEMBL9517194 0.81 KMT2A (0.54) MEN1KMT2A
SCHEMBL9232938 0.81 CDK8 (0.46) NNMT
SCHEMBL19664385 0.81 KMT2A (0.43) ACACBACACAMEN1KMT2A
SCHEMBL9191894 0.80 TSHR (0.39) ACACBACACAKMT2A
SCHEMBL8459579 0.80 PTK2 (0.50) MEN1KMT2A
SCHEMBL9018039 0.80 KDM4E (0.44) ACACBNNMTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861206-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A BINDING POLYMER, METHOD THEREFOR, AND USE THEREOF FOR TREATING HAIR OREAL (FR) 2019-06-12 EP claimed
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 EP claimed
EP-0673932-B1 Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments HOECHST AG (DE) 2000-06-07 EP disclosed
EP-0673931-B1 Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments HOECHST AG (DE) 1997-08-13 EP disclosed
EP-0650961-B1 Substituted heterocyclic carboxylic acid amides, their preparation, and their use as medicaments HOECHST AG (DE) 1997-03-05 EP disclosed
EP-0650960-B1 Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments HOECHST AG (DE) 1997-03-05 EP disclosed
EP-0673931-A1 Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-27 EP disclosed
EP-0673932-A1 Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-27 EP disclosed
EP-0650961-A1 Substituted heterocyclic carboxylic acid amides, their preparation, and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-03 EP disclosed
EP-0650960-A1 Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-03 EP disclosed
EP-0430029-A2 Pyridin-2,4- and 2,5-dicarboxylic acid diamides, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-05 EP disclosed