Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727067 | 1.00 | TSHR (0.49) | TSHRHPGDCXCL12SRD5A2NPC1 | |
| SCHEMBL5023402 | 0.84 | ALDH1A1 (0.46) | TSHRHPGDCXCL12SRD5A2MAPT | |
| SCHEMBL5023406 | 0.84 | ALDH1A1 (0.46) | TSHRHPGDCXCL12SRD5A2MAPT | |
| SCHEMBL5023404 | 0.84 | ALDH1A1 (0.46) | TSHRHPGDCXCL12SRD5A2MAPT | |
| SCHEMBL2235288 | 0.82 | GAA (0.50) | TSHRHPGDNPC1MAPTRAB9A | |
| SCHEMBL2235285 | 0.82 | GAA (0.50) | TSHRHPGDNPC1MAPTRAB9A | |
| SCHEMBL727056 | 0.82 | TSHR (0.57) | TSHRHPGDSRD5A2NPC1MAPT | |
| SCHEMBL726538 | 0.82 | TSHR (0.57) | TSHRHPGDSRD5A2NPC1MAPT | |
| SCHEMBL727057 | 0.82 | TSHR (0.57) | TSHRHPGDSRD5A2NPC1MAPT | |
| SCHEMBL8367177 | 0.78 | KDM4E (0.62) | TSHRHPGDSRD5A2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048896-A | FOR TREATMENT OF BRAIN OR NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-04-11 | — | — | US | disclosed |