Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 12/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.60 |
| ▸ | FAP | Q12884 | 8/20 | 0.60 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.47 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23667668 | 1.00 | DPP4 (0.60) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15500973 | 0.89 | DPP4 (0.48) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL2769142 | 0.83 | DPP4 (0.59) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL25024047 | 0.83 | ACE (0.41) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL10057905 | 0.83 | DPP4 (0.59) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL16670795 | 0.82 | DPP4 (0.57) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8088388 | 0.81 | DPP4 (0.40) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL25757942 | 0.79 | DPP4 (0.39) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL22525831 | 0.79 | DPP4 (0.39) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL20987818 | 0.79 | DPP4 (0.40) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195201-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |
| WO-2012073249-A1 | A NOVEL PROCESS FOR THE PREPARATION OF 3-(BENZYLOXY)- BENZENETHIOL, A KEY INTERMEDIATE FOR THE PREPARATION OF PHARMACEUTICAL DRUGS. | ARCH PHARMALABS LIMITED (IN) | 2012-06-07 | — | — | WO | disclosed |
| US-7834200-B2 | Processes and intermediates | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-11-16 | — | — | US | disclosed |
| WO-2009008913-A2 | P1-NONEPIMERIZABLE KETOAMIDE INHIBITORS OF HCV NS3 PROTEASE | SCHERING CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |