Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 7/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099739 | 0.85 | BDKRB2 (0.42) | BDKRB2KLKB1RAB9APPARGMTNR1A | |
| SCHEMBL8098950 | 0.83 | S1PR4 (0.37) | BDKRB2KLKB1S1PR4PPARGNCF1 | |
| SCHEMBL8097169 | 0.80 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL8106164 | 0.77 | HPGD (0.44) | KLKB1RAB9AALDH1A1HPGD | |
| SCHEMBL6936592 | 0.75 | KDM4E (0.42) | RAB9ANCF1KDM4EALDH1A1 | |
| SCHEMBL6581385 | 0.73 | TP53 (0.42) | S1PR4ALDH1A1HPGD | |
| SCHEMBL6935565 | 0.72 | BDKRB2 (0.46) | BDKRB2 | |
| SCHEMBL8105709 | 0.70 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL8098918 | 0.70 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL8090589 | 0.69 | BDKRB2 (0.59) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795547-B1 | (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as Bradykinin receptor antagonists | HOECHST AG (DE) | 2000-05-10 | — | — | EP | claimed |