Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K8 | P41279 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107127 | 0.83 | KDM4E (0.43) | HTTALDH1A1KMT2ANPSR1TSHR | |
| Ammonia Solution, Strong SCHEMBL8602882 | 0.75 | KDM4E (0.37) | HTTALDH1A1TSHRLMNAMAPT | |
| SCHEMBL11006012 | 0.73 | KDM4E (0.47) | MAP3K8HTTALDH1A1KMT2ATSHR | |
| SCHEMBL13064098 | 0.72 | SELE (0.35) | POLB | |
| SCHEMBL8310208 | 0.71 | KDM4E (0.38) | HTTALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8602879 | 0.71 | SCN4A (0.34) | TSHRLMNACYP2C9 | |
| SCHEMBL1888799 | 0.69 | KMT2A (0.46) | MAP3K8HTTALDH1A1KMT2ANPSR1 | |
| SCHEMBL30828905 | 0.69 | SELE (0.32) | — | |
| SCHEMBL8718664 | 0.69 | SELE (0.32) | — | |
| SCHEMBL8746777 | 0.67 | ACACB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090815-A | Pyrimidinyloxyalkanoic amide derivatives and fungicides for agricultural and horticultural use | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0940392-A1 | PYRIMIDINYLOXYALKANOIC AMIDE DERIVATIVES AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE | KumaiI Chemical Industry Co., Ltd. (JP) | 1999-09-08 | — | — | EP | disclosed |