Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828905 | 1.00 | SELE (0.32) | SELEVCAM1 | |
| SCHEMBL29177511 | 0.92 | SELE (0.35) | SELEVCAM1 | |
| SCHEMBL13064098 | 0.85 | SELE (0.35) | SELEVCAM1 | |
| SCHEMBL8719006 | 0.83 | PDK2 (0.33) | — | |
| SCHEMBL3641399 | 0.79 | SELE (0.40) | SELEVCAM1 | |
| SCHEMBL16712851 | 0.77 | SELE (0.32) | SELEVCAM1 | |
| SCHEMBL2115437 | 0.77 | — | — | |
| SCHEMBL15680396 | 0.76 | GABRA1 (0.32) | — | |
| SCHEMBL8668672 | 0.76 | DHFR (0.36) | SELEVCAM1 | |
| SCHEMBL8491244 | 0.76 | SELE (0.31) | SELEVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217758-A | Preparation method of 6-ethyl-5-fluoro-4-chloropyrimidine | 湖南复瑞生物医药技术有限责任公司 | 2020-06-02 | — | — | CN | claimed |
| EP-0370391-B1 | Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine | LONZA AG (CH) | 1994-11-02 | — | — | EP | claimed |
| US-4977264-A | Condensing 2-chloro-3-oxo-pentanoic acid ester with formamidinium salt, reacting with phosphoryl chloride | LONZA LTD. (CH) | 1990-12-11 | — | — | US | claimed |
| EP-0370391-A2 | Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine | LONZA AG (CH) | 1990-05-30 | — | — | EP | claimed |
| CN-115093396-B | Pyridinylether compound containing pyrimidamine and preparation method and application thereof | 湖南化工研究院有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-113754639-B | Pyridylether compound containing pyrimidinamine and preparation and application thereof | 湖南化工研究院有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-113754638-B | Azaether compound containing pyrimidinamine | 湖南化工研究院有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115093396-A | Pyridine ether compound containing pyrimidinamine and preparation method and application thereof | 湖南化工研究院有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-113754638-A | Azaether compound containing pyrimidinamine | 湖南化工研究院有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-113754639-A | Pyridylether compound containing pyrimidinamine and preparation and application thereof | 湖南化工研究院有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-111217758-A | Preparation method of 6-ethyl-5-fluoro-4-chloropyrimidine | 湖南复瑞生物医药技术有限责任公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-111217758-A | Preparation method of 6-ethyl-5-fluoro-4-chloropyrimidine | 湖南复瑞生物医药技术有限责任公司 | 2020-06-02 | — | — | CN | disclosed |
| US-5523404-A | Process for preparing 5-chloro-4-hydroxypyrimidines | HOECHST SCHERING AGREVO GMBH (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0708758-A1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | Hoechst Schering AgrEvo GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995001963-A1 | METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-19 | — | — | WO | disclosed |
| EP-0370391-B1 | Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine | LONZA AG (CH) | 1994-11-02 | — | — | EP | disclosed |
| US-4977264-A | Condensing 2-chloro-3-oxo-pentanoic acid ester with formamidinium salt, reacting with phosphoryl chloride | LONZA LTD. (CH) | 1990-12-11 | — | — | US | disclosed |
| US-4977264-A | Condensing 2-chloro-3-oxo-pentanoic acid ester with formamidinium salt, reacting with phosphoryl chloride | LONZA LTD. (CH) | 1990-12-11 | — | — | US | disclosed |
| EP-0370391-A2 | Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine | LONZA AG (CH) | 1990-05-30 | — | — | EP | disclosed |
| EP-0370391-A2 | Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine | LONZA AG (CH) | 1990-05-30 | — | — | EP | disclosed |