Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 4/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649339 | 0.77 | ACHE (0.42) | ACHEHRH1HRH4SMN1; SMN2NOS3 | |
| SCHEMBL29439854 | 0.76 | HTR2A (0.55) | ACHEHRH1HRH4SMN1; SMN2NOS3 | |
| SCHEMBL14870745 | 0.76 | HTR2A (0.55) | ACHEHRH1HRH4SMN1; SMN2NOS3 | |
| SCHEMBL32679178 | 0.74 | ACHE (0.59) | ACHESMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL1093558 | 0.74 | ACHE (0.59) | ACHESMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL7338494 | 0.74 | NOS3 (0.44) | ACHEHRH1HRH4SMN1; SMN2NOS3 | |
| SCHEMBL30737574 | 0.74 | ACHE (0.59) | ACHESMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL32679177 | 0.74 | ACHE (0.59) | ACHESMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL8336431 | 0.74 | NOS3 (0.44) | ACHEHRH1HRH4SMN1; SMN2NOS3 | |
| SCHEMBL7998826 | 0.74 | ACHE (0.59) | ACHESMN1; SMN2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763005-B1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0763005-A4 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0763005-A1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5495054-A | REDUCING PROCHIRAL KETONES TO ENANTIOMERICALLY PURE ALCOHOLS WITH BORANE REDUCING AGENT | SEPRACOR, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1995032937-A1 | TETRAHYDROINDENO[1,2-d][1,3,2]OXAZABOROLES AND THEIR USE AS ENANTIOSELECTIVE CATALYSTS | SEPRACOR, INC. (US) | 1995-12-07 | — | — | WO | disclosed |