Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564458 | 0.87 | MAPT (0.54) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25230614 | 0.82 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8095201 | 0.82 | MAPT (0.50) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9564453 | 0.79 | MAPT (0.48) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3435979 | 0.77 | MAPK1 (0.42) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16513957 | 0.77 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29847859 | 0.77 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22471318 | 0.76 | MAPT (0.55) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9564447 | 0.76 | MAPT (0.52) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL24267633 | 0.76 | SIRT6 (0.69) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743848-B1 | 2-FLUORO-6-NITROANILINES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |