Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097435 | 0.87 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25230614 | 0.81 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22471318 | 0.78 | MAPT (0.55) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30464721 | 0.77 | MAPT (0.54) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22471527 | 0.77 | MAPT (0.54) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10571876 | 0.76 | MAPT (0.61) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9564463 | 0.76 | MAPT (0.49) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1000776 | 0.76 | ALDH1A1 (0.50) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL24267633 | 0.75 | SIRT6 (0.69) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28931649 | 0.75 | SIRT6 (0.65) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |