Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104325 | 0.87 | CTSB (0.59) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL1424205 | 0.82 | ALDH1A1 (0.50) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL8097435 | 0.82 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL3984049 | 0.82 | CYP1A2 (0.54) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL30206335 | 0.79 | MAPT (0.57) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL6511388 | 0.79 | MAPT (0.57) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL519289 | 0.77 | CTSB (0.62) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL4140342 | 0.77 | MAPT (0.67) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL10473548 | 0.77 | MAPT (0.54) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL2589998 | 0.76 | MAPT (0.69) | MAPTALDH1A1CYP1A2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743848-B1 | 2-FLUORO-6-NITROANILINES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |