Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078576 | 0.85 | DPP4 (0.37) | DPP4SCN9ACACNA1BAAK1 | |
| SCHEMBL3748312 | 0.84 | DPP4 (0.42) | DPP4KMT2AL3MBTL1RORCSCN9A | |
| SCHEMBL3747829 | 0.83 | DPP4 (0.43) | DPP4KMT2AL3MBTL1RORCSCN9A | |
| SCHEMBL13078880 | 0.79 | ELANE (0.34) | KMT2AL3MBTL1SCN9ACACNA1B | |
| SCHEMBL13078574 | 0.78 | ALDH1A1 (0.35) | DPP4RORC | |
| SCHEMBL7849129 | 0.77 | CYP2D6 (0.38) | KMT2AL3MBTL1CACNA1B | |
| SCHEMBL10060683 | 0.77 | CYP2D6 (0.38) | KMT2AL3MBTL1CACNA1B | |
| SCHEMBL13078813 | 0.76 | CTSK (0.34) | KMT2ACACNA1B | |
| SCHEMBL8092352 | 0.75 | MGLL (0.37) | CACNA1BGPR119AAK1 | |
| SCHEMBL13078578 | 0.75 | CACNA1B (0.37) | KMT2AL3MBTL1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |