Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | RGS4 | P49798 | 1/20 | 0.41 |
| ▸ | RGS8 | P57771 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090603 | 0.87 | LMNA (0.43) | POLBLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8089983 | 0.85 | CA12 (0.38) | POLBLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8098502 | 0.85 | LMNA (0.48) | POLBLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8090122 | 0.84 | MEN1 (0.39) | POLBLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8099315 | 0.83 | NOTUM (0.40) | POLBLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8090426 | 0.83 | LMNA (0.40) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2053916 | 0.82 | MEN1 (0.38) | POLBLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8104045 | 0.81 | NPSR1 (0.46) | POLBLMNAKMT2AMEN1MAPT | |
| SCHEMBL8107067 | 0.81 | ACACB (0.47) | POLBLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8099572 | 0.81 | ACACB (0.47) | POLBLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |