Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099299 | 0.89 | USP2 (0.36) | NPSR1ACACBHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL8107067 | 0.89 | ACACB (0.47) | NPSR1ACACBHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL8099572 | 0.89 | ACACB (0.47) | NPSR1ACACBHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL8106095 | 0.89 | NPSR1 (0.42) | NPSR1ACACBHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL8090122 | 0.89 | MEN1 (0.39) | SMN1; SMN2LMNANPC1TP53MAPT | |
| SCHEMBL8098709 | 0.87 | TRPM8 (0.39) | NPSR1 | |
| SCHEMBL8090426 | 0.87 | LMNA (0.40) | ACACBHSD17B10SMN1; SMN2LMNATP53 | |
| SCHEMBL2053916 | 0.87 | MEN1 (0.38) | ACACBHSD17B10SMN1; SMN2LMNANPC1 | |
| SCHEMBL8090603 | 0.86 | LMNA (0.43) | NPSR1ACACBHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL8106103 | 0.85 | LMNA (0.48) | SMN1; SMN2LMNANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |