Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099572 | 1.00 | ACACB (0.47) | ACACBATML3MBTL1GPR139LIPG | |
| SCHEMBL8090426 | 0.91 | LMNA (0.40) | ACACBMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL8104045 | 0.89 | NPSR1 (0.46) | ACACBMEN1KMT2ATP53HSD17B10 | |
| SCHEMBL8090122 | 0.84 | MEN1 (0.39) | MEN1KMT2AALDH1A1TP53GAA | |
| SCHEMBL8099315 | 0.84 | NOTUM (0.40) | MEN1KMT2AALDH1A1TP53HSD17B10 | |
| SCHEMBL8098502 | 0.84 | LMNA (0.48) | MEN1KMT2AALDH1A1GAAHSD17B10 | |
| SCHEMBL2053916 | 0.82 | MEN1 (0.38) | ACACBMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL8090603 | 0.82 | LMNA (0.43) | ACACBMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8097554 | 0.81 | POLB (0.49) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL8106095 | 0.81 | NPSR1 (0.42) | ACACBTP53HSD17B10LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |