Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24008438 | 0.97 | RAB9A (0.94) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL1046370 | 0.86 | TSHR (0.84) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL5175612 | 0.83 | RAB9A (0.74) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL3567760 | 0.83 | HRH3 (1.00) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL5174712 | 0.82 | RAB9A (0.76) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL2390775 | 0.81 | MEN1 (0.68) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL1044760 | 0.81 | RAB9A (0.91) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL15921120 | 0.81 | SPHK1 (0.78) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL24008777 | 0.81 | RAB9A (0.68) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL3041709 | 0.80 | S1PR5 (1.00) | RAB9AALDH1A1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021224864-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2021-11-11 | — | — | WO | disclosed |
| US-20090023773-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2009-01-22 | — | — | US | disclosed |
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023773-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | TRPV1, TRPV2, TRPA1 | RAB9A 2269/4885ALDH1A1 2694/4885MEN1 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.