Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096918 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL8099152 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HTTLMNAMAPTHPGD | |
| SCHEMBL8098673 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAAHTTKCNH2SMN1; SMN2 | |
| SCHEMBL8098463 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8097385 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8097010 | 0.83 | HPGD (0.37) | ALDH1A1LMNAMAPTHPGDTSHR | |
| SCHEMBL8099202 | 0.81 | L3MBTL1 (0.38) | ALDH1A1GAALMNAMAPTHPGD | |
| SCHEMBL8105972 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8099510 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDTSHRCSNK1E | |
| SCHEMBL8099480 | 0.77 | ALDH1A1 (0.33) | ALDH1A1GAALMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |