Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689752 | 0.84 | WDR5 (0.66) | CYP1A1CYP1B1WDR5KMT2ALDHA | |
| SCHEMBL30791069 | 0.84 | WDR5 (0.66) | CYP1A1CYP1B1WDR5KMT2ALDHA | |
| SCHEMBL5747379 | 0.83 | KDM4E (0.66) | CYP1A1CYP1B1WDR5KMT2AATM | |
| SCHEMBL2831990 | 0.82 | CYP1A1 (0.55) | CYP1A1CYP1B1WDR5KMT2AATM | |
| SCHEMBL8681263 | 0.82 | CYP1A1 (0.55) | CYP1A1CYP1B1WDR5KMT2AATM | |
| SCHEMBL13905710 | 0.82 | CYP1A1 (0.55) | CYP1A1CYP1B1WDR5KMT2AATM | |
| SCHEMBL6748668 | 0.82 | WDR5 (0.68) | CYP1A1CYP1B1WDR5KMT2AATM | |
| SCHEMBL356272 | 0.80 | LDHA (0.69) | CYP1A1CYP1B1WDR5KMT2ALDHA | |
| SCHEMBL29486321 | 0.80 | WDR5 (0.50) | CYP1A1CYP1B1WDR5KMT2AATM | |
| SCHEMBL599946 | 0.80 | WDR5 (0.50) | CYP1A1CYP1B1WDR5KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230101819-A1 | SMYD Inhibitors | EPIZYME INC (US) | 2023-03-30 | — | — | US | disclosed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | Epizyme, Inc. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20170355695-A1 | SMYD Inhibitors | Epizyme, Inc. (US) | 2017-12-14 | — | — | US | disclosed |
| EP-0813112-B1 | Photographic elements containing new magenta dye-forming couplers | EASTMAN KODAK CO (US) | 2000-12-13 | — | — | EP | disclosed |
| EP-0813112-A1 | Photographic elements containing new magenta dye-forming couplers | EASTMAN KODAK COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5670302-A | NAPHTHALENE COMPOUNDS SUBSTITUTED WITH HYDROXYL AND SECONDARY AMIDE GROUPS | EASTMAN KODAK COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | SMYD3, SMYD2, SNRPD3 | CYP1A1 3318/4885CYP1B1 2380/4885WDR5 773/4885 |
| US-20170355695-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | CYP1A1 4126/4885CYP1B1 3243/4885WDR5 1102/4885 |
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | CYP1A1 4161/4885CYP1B1 3325/4885WDR5 1074/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | CYP1A1 3298/4885CYP1B1 2063/4885WDR5 1365/4885 |
| US-20230101819-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | CYP1A1 4182/4885CYP1B1 3348/4885WDR5 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.