Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 9/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099012 | 0.92 | SMPD1 (0.42) | SMPD1PPARGSCN9APTPN1 | |
| SCHEMBL8103943 | 0.92 | SMPD1 (0.42) | SMPD1PPARGSCN9APTPN1 | |
| SCHEMBL8766955 | 0.86 | MGLL (0.39) | SMPD1PPARGSCN9APTPN1 | |
| SCHEMBL8767147 | 0.86 | MGLL (0.39) | SMPD1PPARGSCN9APTPN1 | |
| SCHEMBL8099518 | 0.84 | PPARG (0.40) | SMPD1PPARGSCN9ASCN5A | |
| SCHEMBL8105616 | 0.84 | PPARG (0.40) | SMPD1PPARGSCN9ASCN5A | |
| SCHEMBL8098997 | 0.83 | PPARG (0.45) | SMPD1PPARG | |
| SCHEMBL8875849 | 0.83 | SMPD1 (0.44) | SMPD1PPARGPTPN1 | |
| SCHEMBL8874924 | 0.83 | SMPD1 (0.44) | SMPD1PPARGPTPN1 | |
| SCHEMBL8873798 | 0.83 | SMPD1 (0.44) | SMPD1PPARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673932-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 2000-06-07 | — | — | EP | disclosed |
| EP-0673931-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| EP-0673931-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0673932-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |