Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099518 | 0.94 | PPARG (0.40) | PPARGMEN1KMT2ASMPD1MGLL | |
| SCHEMBL8105616 | 0.94 | PPARG (0.40) | PPARGMEN1KMT2ASMPD1MGLL | |
| SCHEMBL8090622 | 0.90 | SMN1; SMN2 (0.39) | PPARGMEN1KMT2A | |
| SCHEMBL8767147 | 0.89 | MGLL (0.39) | PPARGSMPD1MGLL | |
| SCHEMBL8766955 | 0.89 | MGLL (0.39) | PPARGSMPD1MGLL | |
| SCHEMBL8874879 | 0.87 | MEN1 (0.46) | PPARGMEN1KMT2ASMPD1 | |
| SCHEMBL8767779 | 0.85 | GABRA5 (0.39) | PPARGSMPD1MGLL | |
| SCHEMBL8099332 | 0.85 | MEN1 (0.41) | PPARGMEN1KMT2ASMPD1 | |
| SCHEMBL8806879 | 0.84 | MEN1 (0.43) | MEN1KMT2AMGLL | |
| SCHEMBL8806842 | 0.84 | MEN1 (0.43) | MEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673932-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 2000-06-07 | — | — | EP | disclosed |
| EP-0673932-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |