Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766955 | 1.00 | MGLL (0.39) | MGLLPPARGPTPN1SMPD1SCN9A | |
| SCHEMBL8767779 | 0.96 | GABRA5 (0.39) | MGLLPPARGPTPN1SMPD1SCN9A | |
| SCHEMBL8105616 | 0.90 | PPARG (0.40) | MGLLPPARGSMPD1SCN9A | |
| SCHEMBL8099518 | 0.90 | PPARG (0.40) | MGLLPPARGSMPD1SCN9A | |
| SCHEMBL8098997 | 0.89 | PPARG (0.45) | MGLLPPARGSMPD1 | |
| SCHEMBL8103943 | 0.88 | SMPD1 (0.42) | PPARGPTPN1SMPD1SCN9A | |
| SCHEMBL8099012 | 0.88 | SMPD1 (0.42) | PPARGPTPN1SMPD1SCN9A | |
| SCHEMBL8915786 | 0.86 | EGLN1 (0.42) | PTPN1SMPD1 | |
| SCHEMBL8915832 | 0.86 | EGLN1 (0.42) | PTPN1SMPD1 | |
| SCHEMBL8097631 | 0.86 | SMPD1 (0.42) | PPARGPTPN1SMPD1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673931-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| EP-0673931-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |