Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089737 | 0.83 | PBRM1 (0.43) | PBRM1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL8090521 | 0.83 | ALDH1A1 (0.63) | PBRM1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL8788750 | 0.83 | PBRM1 (0.43) | PBRM1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL8096940 | 0.81 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8089669 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDTSHRPIM1 | |
| SCHEMBL8097655 | 0.79 | ALDH1A1 (0.70) | MAPTALDH1A1HPGDTSHRLMNA | |
| SCHEMBL8089623 | 0.78 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL8090455 | 0.78 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDTSHRHTR2C | |
| SCHEMBL8097793 | 0.78 | ALDH1A1 (0.52) | PBRM1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL8097095 | 0.77 | PIM1 (0.41) | MAPTALDH1A1HPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |