Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097864 | 0.92 | CTSB (0.35) | CTSBCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8083498 | 0.89 | CTSB (0.34) | CTSBHPGDS | |
| SCHEMBL8083599 | 0.88 | CTSB (0.34) | CTSBHPGDS | |
| SCHEMBL8090211 | 0.86 | CTSB (0.33) | CTSBHPGDS | |
| SCHEMBL8091556 | 0.86 | CTSB (0.33) | CTSBHPGDS | |
| SCHEMBL8095180 | 0.86 | ITGB3 (0.32) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL8098190 | 0.85 | CTSB (0.32) | CTSBHPGDS | |
| SCHEMBL8083495 | 0.81 | CTSB (0.35) | CTSBHPGDS | |
| SCHEMBL8083595 | 0.80 | CTSB (0.34) | CTSBHPGDS | |
| SCHEMBL8091555 | 0.79 | CTSB (0.33) | CTSBHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |